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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
12.5 DPC

30 matching records from 30 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pax3  paired box 3   (Synonyms: Pax-3, Splchl2)
Results  Reference
1*J:134595 Anthony TE, Heintz N, The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects. J Comp Neurol. 2007 Jan 10;500(2):368-83
1J:103320 Blake JA, Ziman MR, Pax3 transcripts in melanoblast development. Dev Growth Differ. 2005 Dec;47(9):627-35
1*J:163733 Christova T, Mojtahedi G, Hamel PA, Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription. Int J Biochem Cell Biol. 2010 May;42(5):630-40
1J:159124 Degenhardt KR, Milewski RC, Padmanabhan A, Miller M, Singh MK, Lang D, Engleka KA, Wu M, Li J, Zhou D, Antonucci N, Li L, Epstein JA, Distinct enhancers at the Pax3 locus can function redundantly to regulate neural tube and neural crest expressions. Dev Biol. 2010 Mar 15;339(2):519-27
1*J:72300 Dottori M, Gross MK, Labosky P, Goulding M, The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate. Development. 2001 Nov;128(21):4127-38
1J:98272 Engleka KA, Gitler AD, Zhang M, Zhou DD, High FA, Epstein JA, Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives. Dev Biol. 2005 Apr 15;280(2):396-406
1J:340498 Fernandez-Santos B, Reyes-Corral M, Caro-Vega JM, Lao-Perez M, Vallejo-Grijalba C, Mesa-Cruz C, Moron FJ, Ybot-Gonzalez P, The loop-tail mouse model displays open and closed caudal neural tube defects. Dis Model Mech. 2023 Aug 1;16(8)
1J:147382 Genethliou N, Panayiotou E, Panayi H, Orford M, Mean R, Lapathitis G, Malas S, Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord. Biochem Biophys Res Commun. 2009 Apr 24;382(1):69-73
1J:103319 Horst D, Ustanina S, Sergi C, Mikuz G, Juergens H, Braun T, Vorobyov E, Comparative expression analysis of Pax3 and Pax7 during mouse myogenesis. Int J Dev Biol. 2006;50(1):47-54
1*J:154798 Hueber PA, Fukuzawa R, Elkares R, Chu L, Blumentkrantz M, He SJ, Anaka MR, Reeve AE, Eccles M, Jabado N, Iglesias DM, Goodyer PR, PAX3 is expressed in the stromal compartment of the developing kidney and in Wilms tumors with myogenic phenotype. Pediatr Dev Pathol. 2009 Sep-Oct;12(5):347-54
1J:160733 Ivaniutsin U, Chen Y, Mason JO, Price DJ, Pratt T, Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex. Neural Dev. 2009;4:3
1J:103257 Lacosta AM, Muniesa P, Ruberte J, Sarasa M, Dominguez L, Novel expression patterns of Pax3/Pax7 in early trunk neural crest and its melanocyte and non-melanocyte lineages in amniote embryos. Pigment Cell Res. 2005 Aug;18(4):243-51
1J:197131 Lanctot AA, Peng CY, Pawlisz AS, Joksimovic M, Feng Y, Spatially dependent dynamic MAPK modulation by the nde1-lis1-brap complex patterns Mammalian CNS. Dev Cell. 2013 May 13;25(3):241-55
1J:175545 Lozano-Velasco E, Contreras A, Crist C, Hernandez-Torres F, Franco D, Aranega AE, Pitx2c modulates Pax3+/Pax7+ cell populations and regulates Pax3 expression by repressing miR27 expression during myogenesis. Dev Biol. 2011 Sep 1;357(1):165-78
1*J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
1*J:137604 Minaki Y, Nakatani T, Mizuhara E, Inoue T, Ono Y, Identification of a novel transcriptional corepressor, Corl2, as a cerebellar Purkinje cell-selective marker. Gene Expr Patterns. 2008 Jul;8(6):418-23
1J:305279 Morello F, Borshagovski D, Survila M, Tikker L, Sadik-Ogli S, Kirjavainen A, Estartus N, Knaapi L, Lahti L, Toronen P, Mazutis L, Delogu A, Salminen M, Achim K, Partanen J, Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain. Cell Rep. 2020 Oct 13;33(2):108268
1J:157957 Nakatani T, Kumai M, Mizuhara E, Minaki Y, Ono Y, Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon. Dev Biol. 2010 Mar 1;339(1):101-13
1*J:206666 Parry DA, Logan CV, Stegmann AP, Abdelhamed ZA, Calder A, Khan S, Bonthron DT, Clowes V, Sheridan E, Ghali N, Chudley AE, Dobbie A, Stumpel CT, Johnson CA, SAMS, a syndrome of short stature, auditory-canal atresia, mandibular hypoplasia, and skeletal abnormalities is a unique neurocristopathy caused by mutations in Goosecoid. Am J Hum Genet. 2013 Dec 5;93(6):1135-42
1J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22
1J:119082 Schuster-Gossler K, Cordes R, Gossler A, Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):537-42
1J:224090 Scotti M, Kherdjemil Y, Roux M, Kmita M, A Hoxa13:Cre mouse strain for conditional gene manipulation in developing limb, hindgut, and urogenital system. Genesis. 2015 Jun;53(6):366-76
1*J:117808 Shih HP, Gross MK, Kioussi C, Expression pattern of the homeodomain transcription factor Pitx2 during muscle development. Gene Expr Patterns. 2007 Feb;7(4):441-51
1J:137649 Thompson JA, Zembrzycki A, Mansouri A, Ziman M, Pax7 is requisite for maintenance of a subpopulation of superior collicular neurons and shows a diverging expression pattern to Pax3 during superior collicular development. BMC Dev Biol. 2008;8:62
1J:178971 Valenta T, Gay M, Steiner S, Draganova K, Zemke M, Hoffmans R, Cinelli P, Aguet M, Sommer L, Basler K, Probing transcription-specific outputs of beta-catenin in vivo. Genes Dev. 2011 Dec 15;25(24):2631-43
1J:213846 Zalc A, Hayashi S, Aurade F, Brohl D, Chang T, Mademtzoglou D, Mourikis P, Yao Z, Cao Y, Birchmeier C, Relaix F, Antagonistic regulation of p57kip2 by Hes/Hey downstream of Notch signaling and muscle regulatory factors regulates skeletal muscle growth arrest. Development. 2014 Jul;141(14):2780-90
1J:243678 Zemke M, Draganova K, Klug A, Scholer A, Zurkirchen L, Gay MH, Cheng P, Koseki H, Valenta T, Schubeler D, Basler K, Sommer L, Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation. BMC Biol. 2015 Nov 30;13:103
1J:206311 Zhao T, Gan Q, Stokes A, Lassiter RN, Wang Y, Chan J, Han JX, Pleasure DE, Epstein JA, Zhou CJ, beta-catenin regulates Pax3 and Cdx2 for caudal neural tube closure and elongation. Development. 2014 Jan;141(1):148-57
1J:207050 Zhao X, Huang H, Chen Y, Liu Y, Zhang Z, Ma Q, Qiu M, Dynamic expression of secreted Frizzled-related protein 3 (sFRP3) in the developing mouse spinal cord and dorsal root ganglia. Neuroscience. 2013 Sep 17;248:594-601
1J:243660 Zhu XJ, Yuan X, Wang M, Fang Y, Liu Y, Zhang X, Yang X, Li Y, Li J, Li F, Dai ZM, Qiu M, Zhang Z, Zhang Z, A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development. J Biol Chem. 2017 Jun 02;292(22):9409-9419

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory